In short, No.
If you have the time and patience then, Yes.
APC40's don't have "decks" or "layers"
If you buy a MIDIFIGHTER, iControls, Korg, or other midi device that does have decks, or layers, then yes, it would be easy.
By pressing a deck or layer modifier button, it simply remaps the entire controller front to a new set of midi values.
so deck 1 can be preview and deck 2 can be launch. simply press button (x) in layer 1 to preview it, then press your deck 2 (or sometimes an up or down button) to move to that deck, then press the same button (x) again to launch.
If you have the time and patience, you can install Bomes and build a deck or layer modifier button on your APC40.
lets use the shift button for an example.
You can build a modifier in Bomes that would simply take any midi note that's incoming and would remap it to the same note, 3-4 octaves higher or lower when the shift button is pressed.
You could even build a modifier in Bomes that would make the shift button a (resolume style) "piano" button, or momentary switch, rather than a standard on or off switch, so you could just hold the shift button down and preview, rather than pressing and releasing shift, then previewing, then pressing and releasing shift again to play the clip.
This is completely separate from Resolume as it's a different program though. So support for building hex syntax's would be better found on the Bomes forums. Or you could just buy a controller with a deck's or layers modifier button built in.
Personally, I prefer to look at what i'm turning on and off (ie. looking at my gui rather than just pressing buttons on a controller to see what clip I get), So I personally never fire clips from a controller, only fx and clip modifiers. I like to see the clips on my gui and fire them with my touch screen or a mouse.
Hope some of this info helps?