Same here, I've used Qlab OSC on many shows and never had a missed cue.I'm using the same showcontrol workflow like you: Qlab OSC over a wired network to a Mediaserver with Resolume. I havn't ever experienced a packet loss over a wired network but I do have over wireless connection (even 5ghz).
I can't personally think of a case where triggering the same column twice in a row would be acceptable!But anyway: let's say we're triggering a column, Resolume will play the first frame of the movie twice I guess. That might be acceptable, right?
--
David, I understand you're using a wired network for your setups but are you turning off the wireless adapter on your mac?
Also, I never trust network architecture in any theatre and always bring my own equipment. That way 1) I know exactly what I'm dealing with and 2) I can easily troubleshoot. As a note, for runs over 100ft I use CAT6a solid core copper ethernet cables instead of stranded.
Have you ever tried Zoltàn's Linear OSC Controller? I think for what you do, it's probably better suited than Qlab. It's a very fluid process because it uses the same XML file so you can make changes in either Resolume or Linear OSC Controller. It also gives you tons of added discrete control such as changing the layer transition times between column triggers!