I'm having the same problem...
Normal, fullscreen output seems fine, but any time I've run the advanced output with slices etc... on v 4.1 - 4.1.4 for longer than 2 hours or so, I crash.
I've suspected all along that it has something to do with the advanced output on my setup, but I've currently eliminated all effects per tech support's sugestion.
I've got 2 clips running right now to 7 slices.
I'll post back in a few hours.
Windows 7 (64bit)
Lenovo Ideapad Z570
NVIDIA GeForce GT 630M
Intel i5 quad core 2.5ghz / 6GB Ram
Hitachi 500GB 5400 RPM 8MB Cache 2.5" SATA 3.0Gb/s