Mike at TrackTeam Audio has made a Monome emulator for the APC40 (
http://www.trackteamaudio.com/#3), that is basically a MIDI to OpenSoundControl translator.
It supports full LED feedback on the buttons, and he is still working on LED feedback on the knobs.
Since he makes the full source (in Max/MSP) available, and since Resolume uses OpenSoundControl, it seems that it would be possible to set up a very flexible and powerful control mapping - better than attempting to MIDI learn the APC40's fixed MIDI setup.
However, since Resolume does not yet output MIDI or OSC, full two-way feedback might be tricky. (However, implementing OSC out from Res should be easy, right, Bart & Edwin?)