No, it’s more like an desync while strobe effects.
I could solve the problem in any other software by enabling artnet sync, especially when I am using more than one controller.
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Resolume does not currently support ArtNet VSync. We have issue #6938 for this in our features bucket, but it does not have a date scheduled to it. So for now your best choice is probably to route our output through a controller with syncing capabilities.