I have used the Microsoft LifeCam HD-6000 on a Mac Mini with no issues whatsoever. It was completely plug and play, and the camera appeared in the Sources menu. Latency was undetectable, identical to BMD cards. And I was just messing around on a comp with the Intel integrated GPU.
While I was using a 720p model, I *would imagine the 1080p model in the LifeCam series would be just as easy to set up and use. There may be more latency, but probably just 1-2 frames.